鸡支原体对氟喹诺酮类药物的耐药判定标准研究现状

doi:10.11843/j.issn.0366-6964.2018.02.002

Abstract

Abstract:

With the extensive and unreasonable use of fluoroquinolones in the treatment of Mycoplasma gallisepticum disease, the drug resistance of Mycoplasma on fluoroquinolone becoming more and more serious. In order to regulate the application of fluoroquinolones in the treatment of Mycoplasma disease and to reduce the occurrence of drug resistance to a certain extent, it is necessary to develop the standard of resistance to Mycoplasma gallisepticum on fluoroquinolones. The author introduces the definition and formulation process centered on the criteria for drug resistance, and summarized the related studies on the determination of resistance to fluoroquinolones in Mycoplasma at home and abroad, including wild type Cutoff, PK-PD Cutoff and clinical Cutoff. Finally, the shortcomings of the current researches were reviewed and put forward our own ideas, in order to provide a reference to slow down the resistance of Mycoplasma gallisepticum to fluoroquinolones.

CLC Number:

S852.62

WANG Shu-ge, GU Yu-feng, HUANG Ling-li, HUANG An-xiong, WANG Xu, LIU Zhen-li, HAO Hai-hong, YUAN Zong-hui. Establishment on the Susceptibility Breakpoints Standards for Fluoroquinolones against Mycoplasma gallisepticum in Chickens[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2018, 49(2): 231-242.

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Establishment on the Susceptibility Breakpoints Standards for Fluoroquinolones against Mycoplasma gallisepticum in Chickens

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